Novel Reversible Fluorescent Glycan Linker for Functional Glycomics
نویسندگان
چکیده
منابع مشابه
Novel fluorescent glycan microarray strategy reveals ligands for galectins.
Galectin-1 (Gal-1) and galectin-3 (Gal-3) are widely expressed galectins with immunoregulatory functions in animals. To explore their glycan specificity, we developed microarrays of naturally occurring glycans using a bifunctional fluorescent linker, 2-amino-N-(2-aminoethyl)-benzamide (AEAB), directly conjugated through its arylamine group by reductive amination to free glycans to form glycan-A...
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ژورنال
عنوان ژورنال: Bioconjugate Chemistry
سال: 2019
ISSN: 1043-1802,1520-4812
DOI: 10.1021/acs.bioconjchem.9b00613